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THE INFLUENCE OF TIA-1 ON HSV-1 REPLICATION. ICP34.5 AND TIA-1 INDUCED STRESS GRANULES

Автор:   Rajasekhar S.
мягкая обложка
60 страниц
2009 год
Издательство:   Книга по Требованию
Цена:
1978 руб
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Описание:Herpes simplex virus-1 (HSV-1) and Herpes simplex virus-2 (HSV-2) are large, enveloped DNA viruses. They were the first human herpes viruses to be discovered and are amongst the most intensively investigated. Prof. Kenneth Rosenthal's lab has demonstrated that differences in virulence and tissue culture behavior for some HSV-1 strains can be attributed to variation in the ICP34.5 gene and protein. ICP34.5 binds to PP1 to dephosphorylate eIF2alpha and stop HSV induced ER stress and inhibition of protein synthesis. T-cell like intracellular antigen-1 (TIA-1) and its closely related protein TIAR, are cellular proteins belonging to the RNA-recognition motif (RRM) family of RNA binding proteins. They are essential for normal vertebrate development and act as gene translational silencers. They play an important role in the formation of stress granules during abortive protein translation when eIF2alpha is phosphorylated by PKR or PERK and protein synthesis is stalled. This research study demonstrates the ability of TIA- 1 to limit HSV-1 viral replication.


Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка

2990 руб
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Journeys out of the body, Practical Guidebook

Phase entry is a very profound, incredible experience that may induce fear, which is invoked by a natural instinct for self-preservation. The phase can create stress. This is especially true for novices and those poorly acquainted with the nature of the phenomenon and techniques used to control it. Without knowledge and proper practice, a fear-induced reaction can escalate into full-blown terror. After all, while in the phase, fantasy quickly becomes reality, and reticent fears can take on hyper-realistic qualities. When this occurs, itБЂ™s not the phase environment, but the fear that is treacherous. It goes without saying that fear is a toxic influence, especially to sensitive souls, the elderly, and people with physical ailments, like certain cardiovascular conditions. This does not mean that persons in these groups should abstain from practicing the phase. The solution is to learn about and avoid common stressors associated with the practice, know the mechanics of controlling objects, and understand the principles of making an emergency exit ...»

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Настольная семейная игра "Звонкие колечки".
Эта игра создана для того, чтобы улучшить умственную и зрительную реакцию малышей. Внутри вы найдёте колечки 6 разных цветов и звонок.
362 руб
Раздел: Карточные игры
Трехколесный велосипед Funny Jaguar Lexus Racer Trike (цвет: бронза).
Детский трехколесный велосипед с колясочной крышей на колесах ПВХ – настоящее спасение для мам с маленькими детьми. Главное место для
3600 руб
Раздел: Трехколесные
Карандаши цветные, трехгранные, 18 цветов.
Один цвет желтый - флюо! Мягкие, но при этом очень прочные карандаши, легко затачиваются и не крошатся. Насыщенные штрихи на бумаге. Не
305 руб
Раздел: 13-24 цвета


How To Win Friends And Influence People (Как завоевывать друзей и оказывать влияние на людей): Книга для чтения на английском языке Original reading English ISBN 5-89815-538-4
          146 руб             2005 год          368 стр.          Мягкая обложка

Fashion icon: the power and influence of graphic design / Модная энергия
From what&s hot in type to the coolest new colour, to the style and mood of the moment, the fashion world sets the tone and the look for the wider design community. This volume presents a diverse portfolio of innovative design work inspired by cutting-edge fashion trends. It features fashion examples from print advertising (magazines), retail space (store displays), packaging (boxes and bags) and more. Each photograph is accompanied by a description of materials used in the design and sidebar features explore the role of industry players such as art directors, photographers, models, magazine editors and stylists. When it comes to trends no segment of the design world is more powerful, more influential or more closely watched than fashion.
          2 руб             176 стр.          твердый переплет

Flax Culture: An Outline Of The History And Present Condition Of The Flax Industry In The United States And A Consideration Of The Influence Exerted On It By Legislation (1888)
          598 руб             1888 год          102 стр.          мягкая обложка

The Influence Of The Drama (1913)
          593 руб             1913 год          136 стр.          мягкая обложка

The Influence Of Wealth In Imperial Rome
          2 руб             350 стр.          мягкая обложка

American Meat And Its Influence Upon The Public Health (1910)
Print-on-Demand - это технология печати книг по Вашему заказу на цифровом типографском оборудовании.
          1139 руб             1910 год          218 стр.          мягкая обложка

The Battle of the Soul in Sir Gawain and the Green Knight. The Influence of Mystical Theology on the Artistic Conception of the Gawain-poet
          1978 руб             2009 год          76 стр.          мягкая обложка

Influence of zinc on the normal and ischaemic retina. In vitro and in vivo studies
When very low (1 micromolar) concentrations of ZnSO4 were present during ischaemia, GABA-immunoreactivity was localised to Mueller cells, indicating that zinc prevents the metabolism of GABA in Mueller cells in the ischaemic retina.
          2744 руб             2009 год          188 стр.          мягкая обложка

Recommender Systems based on Personality Traits:. Could human psychological aspects influence the computer decision-making process?
Nevertheless, the psychological aspects have, unfortunately, not been highly applied in Recommender Systems during their decision-making process.
          2382 руб             2009 год          148 стр.          мягкая обложка

L.D. White: Scholar and Practitioner. The Intellectual Influence of Leonard D. White On The Field Of American Public Administration
This shift represented a change from the classical model of administration to a focus on organizational decision making.
          3188 руб             2009 год          204 стр.          мягкая обложка

An assessment of the factors that will influence the establishment of a viable nursery in Elim The establishment of a viable nursery in Elim.
Examining the factors that will influence the establishment of a viable nursery in Elim, a rural area abundant with natural fynbos species, can aid in identifying and addressing the elements that are required to contribute to economically viable agribusinesses and provision to poor households.
          1994 руб             2009 год          84 стр.          мягкая обложка

LINKING THEORIES LINKING NETWORKS. SOCIAL INFLUENCE AND STATUS CHARACTERISTICS
Biography and sociology can be related in organizational and historical processes.
          1994 руб             2009 год          116 стр.          мягкая обложка

Ethnic and Male/Female Diversity and the Performance of European Banks. Can Ethnic and Male/Female Diversity Influence the Financial Performance of European Global Banks?
This investigation tests the theory using a questionnaire and statistical analysis followed by a qualitative investigation using the same variables.
          1994 руб             2009 год          88 стр.          мягкая обложка

The Influence of Conflicting Perspectives on Children's Memory. Conflicting Perspectives and Memory
Story 1 was designed to evoke a negative interpretation of the best friend’s behaviors such that the participant would most likely conclude that the best friend was mean-spirited.
          2766 руб             2009 год          180 стр.          мягкая обложка

Enhancing Pupils' Critical Understanding of Mass Media Texts. The Influence of Art on Pupils' Creative Expression and Critical Understanding of Mass Media Visual Texts
The Six Conceptual Values were employed in workshops for school pupils, enhancing understanding and critical awareness of media texts, and enabling assessment of the pupils' work. The book provides clear guidelines for educators in the Arts and Media and Communication studies including assessment of pupils' achievements. Young people have become detached from the arts, becoming passive consumers, rather than expressing thoughts in autonomous creative activities.
          3212 руб             2009 год          432 стр.          мягкая обложка

Crosslinguistic Influence in L2 Acquisition and in Creole Genesis. A Handbook
It is the social and historical circumstances that accelerated the changes and allowed interlanguage structures to fossilize and to create a new language from the linguistic chaos of plantation societies.
          3212 руб             2009 год          236 стр.          мягкая обложка

On the influence of non-perfect randomness on probabilistic algorithms
The second part of this work examines the impact of various sources of randomness on the quality of the solution of probabilistic optimization heuristics, concentrating on Simulated Annealing as an example for local search heuristics and a genetic algorithm as an instance of population based heuristics.
          3212 руб             2009 год          156 стр.          мягкая обложка

Spin State Switching Triggered by Light. Both Spacer Length and Parity Influence the Thermal and Light-Induced Properties of Spin Crossover Coordination Polymers
The results allow a deeper insight in coherences between structural changes and electronic occupations, which can be detected as thermal, optical or magnetic spin transitions.
          3212 руб             2008 год          160 стр.          мягкая обложка

An Examination of the Influence of Reading Incentive Programs and Activities - A View from the Elementary School Developing Middle School Readers.
The results concluded: (a)reading programs and activities that students are exposed to in elementary school may not correlate with high scores on a standardized reading test; (b) high scores on a standardized reading test may not correlate positively with a positive attitude about reading; (c) although there is no specific program that will guarantee high scores on a standardized reading test, schools should consider a combination of reading programs and activities.
          2413 руб             2008 год          128 стр.          мягкая обложка

Captive Insurance Companies and Their Influence on the Risk Management and the Rating of the Parent Company Captive Insurance Companies in Risk Management.
The theoretical and practical approaches used in this book will give the reader a solid understanding of the function and use of captives in risk management.
          2005 руб             2008 год          68 стр.          мягкая обложка

Influence of Individual Differences on Choice Strategies Consumer Decision Behavior in Online Shopping Environments.
In Consumer Decision Behavior in Online Shopping Environments, the authors examine the consumer' s decision-making process in Internet shopping. The authors analyze the relationship between individual characteristics and decision strategies and, propose that prior Internet shopping experience, self-perceived information processing ability, and perceived interactivity influence the consumer’s strategy preference. A two-phase experiment is presented, and detailed descriptions of online marketing strategy and tactics are also included. Unlike shopping at brick-and-mortar stores, where the consumer receives product information or advertising messages in a more passive way, the online shopping environments require the consumer to be actively involved in searching for and comparing information. The emergence of the Internet has resulted in the change of consumer information process.
          2005 руб             2009 год          180 стр.          мягкая обложка

A Numerical Study on the Influence of Different Bearing Systems Base-isolated Bridges Under Seismic Loads.
The specific purpose of the study is to assess the effect of seismic isolation on the peak response of bridges subjected to different base accelerations ranging from 0. 05 g to 0. 5 g in the horizontal direction transversal to the bridge axis.
          2005 руб             2008 год          116 стр.          мягкая обложка

Stability and Democratization: A Spanish Model?. Political, Economic and Social Factors that Influence Stability During a Democratic Transition
The case of Spain is studied in detail because of the possible insight that may be gained by examining a transition from authoritarianism that overcame many destabilizing factors and ended in the apparent success of democratic consolidation.
          2005 руб             2008 год          120 стр.          мягкая обложка

“THE DEVELOPMENT OF IRAQI OIL PRODUCTION 1972-2003“. The Iraqi Oil Industry under the Influence of Saddam Hussein
Saddam Hussein represented the policy of the Warsaw Pact in his own country and in the Middle East.
          2781 руб             2009 год          200 стр.          мягкая обложка

The Influence of Individual Characteristics, Situational Circumstances and Emotional Experiences in Consumers’ Ethical Decision-Making Processes Understanding Ethical Consumer Behavior.
More specifically, the impact of 1/ individual characteristics (personal values), 2/ situational circumstances (relationship marketing), and 3/ emotional experiences (guilt) within the ethical decision-making processes of consumers are investigated.
          3231 руб             2008 год          452 стр.          мягкая обложка

Cultures of Mobility. New Global Nomadism, Third Culture, and the Influence of Study Abroad
It addresses a particular aspect of globalization, that of mobility, and exemplifies how it is changing some of the traditional concepts of culture and identity, such as with these "New Global Nomads".
          2005 руб             2009 год          48 стр.          мягкая обложка

The Necessity of simultaneous Development, Protection and Exploitation The Influence of intangibe Assets on the Value of a Company.
Still, most of them and their influences are not identified.
          2005 руб             2009 год          68 стр.          мягкая обложка

Influence of Hidden Curriculum on Career Choice. THE DEUTSCHE-SCHULE-ISTANBUL
Given this fact, it is of interest to ask why students graduating from particular schools differ in their career choice.
          2781 руб             2009 год          168 стр.          мягкая обложка

Effects of Family Influence on Satisfaction with Financial Results. Family business examined using the Family-Power, Experience, Culture (F-PEC) Scale on the 2002 American Family Business Survey data set
This study empirically tests the validity of the F- PEC scale developed by Astrachan, Klein and Smyrnios (2002) and, using structural equation modeling, concludes family experience and culture have a statistically significant, positive relationship with satisfaction with financial performance in family business.
          2413 руб             2009 год          148 стр.          мягкая обложка

The Adams Influence Model (AIM). Understanding the factors, attributes and process of achieving influence
In this capacity, the CNE is the gatekeeper for the advancement of the majority of the 2. 4 million nurses practicing in the U. S. Literature suggests that early CNEs lacked influence and often were not recognized members of organizational executive teams.
          2413 руб             2009 год          144 стр.          мягкая обложка

Системы питания, системы зажигания двигателей легковых автомобилей: Карбюраторы 'Озон', 'Вебер': Пособие (под ред. Шленчика Т. А. ; сост. Быков К. П. ) - 72 с. Топливные насосы; Устройство, регулировка, ремонт:
          37 руб             `03 год

Карбюраторы "Озон". Поиск и устранение неисправностей, регулировка и доработка, все модификации Обслуживание и ремонт.
Подробно рассмотрены возможные неисправности, их причины и способы устранения.
          123 руб             2007 год          96 стр.          мягкая обложка

Карбюраторы 'Озон': Практическое руководство для любителей и специалистов - 88 с. ISBN 5-88462-071-3 ~54.00.00 40023
          32 руб             `03 год

Устройство, регулировка, эксплуатация и ремонт (под науч. ред. Погребного С. Н. ) - 64 с. Карбюраторы 'Озон':
          57 руб             03/01/00 год

Практическое пособие - 64 с. Устройство, ремонт, регулировка: Карбюраторы 'Озон':
          45 руб             03/99/98 год

Выпуски 1-8 (количество DVD дисков: 8) DVD. Смешарики. Все серии! Часть первая.
Остроумные сюжеты и симпатичные герои этого популярного сериала нравятся всем, кто ценит добродушный юмор и оптимизм.
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DVD. Приключения кота Леопольда. Все серии
Автомобиль кота Леопольда Клад кота Леопольда 4.
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DVD. Смешарики. Все серии! Часть вторая. Выпуски 9-16 (количество DVD дисков: 8)
Не пропустите вторую часть уникального собрания выпусков знаменитых Смешариков, которых обожают все дети в нашей стране и за ее пределами!
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DVD. Смешарики. Все серии! Часть третья. Выпуски 17-24 (количество DVD дисков: 8)
Целых 8 выпусков мультфильмов о Смешариках под одной обложкой!
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DVD. Фиксики. Все серии с песнями!
Кроме серий, диск содержит бонусные видеоклипы с караоке-титрами.
          106 руб   

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