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Andrographolide - A potential anti-prostate cancer agent. Stay close to nature - it will never fail you

Автор:   Guak-Kim T.
мягкая обложка
220 страниц
2009 год
Издательство:   Книга по Требованию
Цена:
3231 руб
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Описание:Selective cytotoxicity, a concept of killing cancer cells while sparing normal cells, is the Holy Grail in cancer treatment. As part of our search for selective cytotoxic compounds from local plants, andrographolide extracted from A. paniculata was found to be selectively cytotoxic against postate cancer (PC-3) cells without significant toxicity to normal cells. Andrographis paniculata, locally known as “hempedu bumi”, is a small shrub that grows abundantly in Southeast Asia. The bitter taste is due to andrographolide, a furano diterpene that exerts most of the biological poperties. To the best of author' s knowledge, this is the first study that demonstrates the morphological and biochemical changes occurring in PC-3 cells after treatment with andrographolide. In particular, the results suggested that andrographolide-induced cell death in PC-3 cells was achieved through the apoptotic pathway, via the activation of an extrinsic caspase cascade. It is widely used for the treatment of diabetes, rheumatism, hypertension and dysentery. Prostate cancer is the second leading cause of male cancer deaths after lung cancer among American men.


Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка

2990 руб
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Abused again and again

He rested his entire weight on her body as he breathed heavily. Finally he pushed himself away and sat up. "You're a good piece of ass. It's too bad I won't be seeing you anymore." Panic pounded suddenly in Ginger's heart. No! She couldn't lose Roger. She had done too much to lose him now. "No," she begged. "Don't leave me, Roger." "What good are you to me," he said. "You haven't done half of the things I expected you to do here. From the reports I've gotten, the only thing you ever wanted to do was get away." "Come with me, Roger. I love you. We don't need these people. We can go somewhere else. We can hide. The police will never find you." Roger laughed. "You don't still believe that story, do you? The police were never after me. That was just what I told you to get you down here." He stood up and rubbed his cock back and forth between his palms. He picked up his clothes and began dressing. "There's only one way we can stay together and you've already shown you're not fit for that." "But I love you, Roger. Please, go away with me ...»

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Развивающая игра "Чудо - молоток".
Игра развивает творческий потенциал ребенка, способствует тренировке мелкой моторики, внимания, памяти. Играть в нее можно как одному,
1053 руб
Раздел: Прочие
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Головоломка Орбо – это абстрактная головоломка в виде белого шара с разноцветными шариками внутри. Она понравится как детям, так и
616 руб
Раздел: Головоломки
Пробковая доска с деревянной рамкой SP, 60х40 см.
Пробковые доски, тип SP применяются в качестве персональных информационных дисплеев. На их поверхность с помощью кнопок или булавок можно
722 руб
Раздел: Прочее


Novel Therapeutic Agents for the Treatment of Prostate Cancer. Design and Development of Novel Anti-androgens, Thapsigargin Analogs and Inhibitors of Prostate Specific Antigen
Specifically, we have discovered and designed a diverse array of novel molecules targeting the AR signaling pathway, the sarco-endoplasmic reticulum calcium ATPase pump driven calcium homeostasis and the proteolytic activity of prostate specific antigen .
          2781 руб             2008 год          196 стр.          мягкая обложка

Novel Hardware and Software approaches for prostate cancer classification using Multispectral Images Prostate Cancer Classification using Multispectral Images.
For such a high dimensionality, pattern recognition techniques suffer from the well-known curse of dimensionality problem along with increase in execution time.
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Anti-apoptotic and Pro-inflammatory Signaling in Cancer Cells. Status and Modulation by Chemotherapeutic Drugs
It was shown that this reduction was due to drastic downregulation of TNF-receptor 1 by HDIs.
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The book will describe novel antifungal agents, its targets, and various development phases and potential benefits of combination therapy.
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The Secret Agent
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Breast Cancer Care Short Story Collection The Book Lovers' Appreciation Society:
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Cancer Ward
Withdrawn from publication in Russia in 1964, it became, along with One Day in the Life of Ivan Denisovich, a work that awoke the conscience of the world.
          1149 руб             2003 год          576 стр.          мягкая обложка

Detection of Early Features of Cancer in Mammography. Image Analysis and Computer Aided Diagnosis
The detection of breast masses in temporal mammographic pairs is also investigated.
          3188 руб             2009 год          260 стр.          мягкая обложка

Gene therapy of bladder cancer and colorectal metastasis in the liver. Isulin like growth factor 2 P3 and P4 regulatory sequences controlled suicidal therapy of cancer cells
This book describes a PhD research in which the regulatory sequences of IGF2 (P3 and P4 promoters) were used to induce killing of cancer cells in culture or cell of mouse and rat bladder TCCs and of rat colon metastasis to the liver.
          2382 руб             2009 год          156 стр.          мягкая обложка

The Effect of Test Features on the Willingness of Medical Experts and Patients in Germany and the US to Use Colorectal Cancer Screening Tests Acceptance of Colorectal Cancer Screening Tests.
Three groups of people are normally involved in screenings for colorectal cancer and were asked for their feedback about these tests: patients (undergoing the tests), practitioners (performing most of the tests), and laboratory experts (analyzing some of the tests).
          2744 руб             2008 год          204 стр.          мягкая обложка

Characterization of Hyperpolarized Xe-129 NMR Spectra. Characterization of Hyperpolarized Xe-129 Dissolved in Perfluorooctyl Bromide Emulsions as a Novel Magnetic Resonance Contrast Agent
H-Xe dissolved in PFOB emulsions stabilized with egg-yolk phospholipid (EYP) has been suggested as a possible in vivo NMR contrast agent.
          1978 руб             2009 год          100 стр.          мягкая обложка

Emotions: psychology, logical formalisation, and agent applications. A BDI logical formalisation of a psychological theory of emotions, and its implementation in agent applications
The second part is dedicated to the logical formalisation of emotions; it introduces the logical framework, exposes and argues the formal definitions of twenty emotions, and proves some of their properties.
          3212 руб             2009 год          216 стр.          мягкая обложка

The Effects of Teachers’ Feedback on Students’ Ability to Self-Edit. Potential Benefits of Teachers’ Corrective Feedback in L2 Classes
Yet, one issue of concern for most ESL language teachers and educators has not been thoroughly examined which is how “explicit” the error feedback should be in order to help students self-edit their texts.
          1994 руб             2009 год          64 стр.          мягкая обложка

Comparing cancer survival using population-based cancer registry data. methods and applications
Interpretation of comparative survival from population-based cancer registry data is generally not easy.
          2400 руб             2009 год          140 стр.          мягкая обложка

The Eastern Enlargement of the EU and the Cohesion Countries. Commodity Composition of Trade in Manufactures and Trade Potential
A gravity model is used to evaluate the manufacturing trade potential of the Central and Eastern European Countries (CEEC) with the EU15 countries from 1999 to 2002.
          3212 руб             2009 год          236 стр.          мягкая обложка

The Potential Impact of Legalizing Marijuana. An Examination with Respect to Health, Crime, and Economy
It offers an impartial overview about what aspects need to be taken into account when debating on drug legalization.
          1994 руб             2009 год          80 стр.          мягкая обложка

Potential of Blanquilla pear variety for producing pear spirits. Influence of the raw material, the fermentation and the distillation conditions in the final quality of the spirits
The research has been focused in the influence of three main aspects: the raw material used, the fermentation process, and the distillation process.
          3212 руб             2009 год          204 стр.          мягкая обложка

Modeling Cancer Progression on the Pathway Level. Assessing Cancer Progression via Pathway Dependencies
The results may provide insight that will lead to treatments and preventions.
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Spicing up Software-Intensive Systems with CurCuMA. A Model-Driven Approach to Multi-Agent System Design
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Data Analysis with R Modelling Recurrent Event Data with Application to Cancer Research.
Modern techniques such as penalized likelihood approach, nonparametric smoothig and bootstrapping are developed and used when appropriate.
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Theory and Application A Component-Based Multi-Agent System Modeling Methodology.
The main contributions of the research are : 1) defines a new feature called a potential arc that is used to extend traditional Colored Petri Net (CPN) models to support agent behavior modeling; 2) presents a semi-automated MAS modeling methodology, which allow software engineers to create MAS systems based on the extended CPN model; 3) presents an intelligent coordinator design methodology, resulting in a set of coordinators at different levels of intelligence; and 4)evaluates the proposed modeling methodology by developing models and performing simulationbased analysis. The research reported in this dissertation involves a broad array of tasks, including model generation algorithms, analysis/simulation techniques, and experimentation. Potential arcs serve to extend the traditional CPN model with an explicit support for distinguishing the representation of potential conflicts and real conflicts, and thereby avoid the need for eliminating all potential conflicts in the design stage. This dissertation defines a new feature called a potential arc that is used to extend traditional Colored Petri Net(CPN) models to support agent behavior modeling.
          2400 руб             2009 год          144 стр.          мягкая обложка

Polymer Cholesteric Liquid Crystal Flakes. Their Electro - Optic Behaviour for Potential E - Paper Application
Maxwell-Wagner polarization was confirmed to be the main mechanism for the flake reorientation in an electric field.
          3231 руб             2008 год          276 стр.          мягкая обложка

Das Principal-Agent-Problem in den Fuehrungsstrukturen. Eine oekonomische Analyse innerhalb des Sportvereins
Im vorliegenden Buch wird erlaeutert, inwiefern Erkenntnisse aus der Principal-Agent-Theorie auf den ehrenamtlich gefuehrten Sportverein uebertragbar sind.
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Exploring Differences in Breast Cancer Prognostic Factors. Health Disparities between Caucasian and African-American Women in the United States
Differences in breast cancer age at diagnosis, histology, and stage are present by race.
          2005 руб             2008 год          88 стр.          мягкая обложка

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