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Total Synthesis of Callipeltin E and Towards Papuamide B. Syntheses of Anti-HIV

јвтор:   SELCUK C.
м€гка€ обложка
128 страниц
2008 год
»здательство:    нига по “ребованию
2413 руб
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ќписание:The novel structural features and diverse biological effects of these peptides metabolites have generated considerable interest among synthetic chemistry groups. In this book, discovery of the lanthanide catalyzed transamidation of Fmoc protected lactams, solid-phase synthesis and configurational reassignment of Callipeltin E, synthesis of N-Fmoc- (2S,3S,4R)-3,4-dimethylglutamine and an efficient method for the on-resin synthesis and macrocylization of a simplified Papuamide B model system are summarized. Callipeltins and Papuamides -novel families of cyclic depsipeptides- were shown to possess potent anti-HIV activity as well as cytotoxicity against several multidrug resistant cancer cell lines.

Orthomol Immun Junior —ила иммунитета на страже ¬ашего ребенка Orthomol Immun Junior —ила иммунитета на страже ¬ашего ребенка

2990 руб
Ѕесплатна€ доставка

Bad Science

When you read a dramatic claim like HolfordЅАЩs, you might assume itЅАЩs based on some kind of study, perhaps where people with AIDS were given vitamin C. ThereЅАЩs a little superscript ЅАШ23ЅАЩ, referring you to a paper by someone called Jariwalla. With bated breath I grabbed a copy of this paper online. The first thing I noticed was that this paper does not mention ЅАШAZTЅАЩ. It does not compare AZT with vitamin C. Nor does it involve any human beings: itЅАЩs a laboratory study, looking at some cells in a dish. Some vitamin C was squirted onto these cells, and a few complicated things were measured, like ЅАШgiant cell syncytia formationЅАЩ, which changed when there was lots of vitamin C swimming around. All well and good, but this laboratory-bench finding very clearly does not support the rather dramatic assertion that ЅАШAZT, the first prescribable anti-HIV drug, is potentially harmful, and proving less effective than vitamin C.ЅАЩ In fact, it seems this is yet another example of that credulous extrapolation from preliminary laboratory data to clinical claim in real human beings that we have come to recognise as a hallmark of the ЅАШnutritionistЅАЩ ...»

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Ќабор маркеров дл€ досок "E-361", 1 мм, 8 цветов.
ћаркеры дл€ написани€ и маркировки текста на белых досках. —тираетс€ сухой губкой почти со всех плотных поверхностей, например, эмали,
592 руб
–аздел: ƒл€ досок
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ћаленькие гонщики в возрасте от 1 до 3 лет будут в восторге от маневренной машинки "¬ихрь". Ћегка€ и неверо€тно проста€ в
1350 руб
–аздел:  аталки
ѕеленка ѕапитто фланелева€ (3 штуки, 120x75 см).
—остав: фланель импортна€ (хлопок 100%). –азмер: 120x75 см. –асцветка в ассортименте, без возможности выбора.
466 руб
–аздел: ѕелЄнки

The Development of New Methods toward Guaiane Natural Products. The Use of Irontricarbonyl Cyclobutadiene in Total Synthesis
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Steady state catalytic activity is positively correlated with increasing bulk chi-carbide content for silica-supported Fe and FePt catalysts but not for FePtK.
          2382 руб             2009 год          152 стр.          м€гка€ обложка

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Formant Based Speech Synthesis. Synthesizing Amharic vowels
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Metal complexes of N-heterocyclic carbene. Silver, mercury, ruthenium and palladium complexes of N-heterocyclic carbene-linked cyclophanes: synthesis, molecular structures and characterization
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P/M technology can be used to refine microstructures compared with those made by conventional ingot metallurgy, which often results in improved mechanical and corrosion properties.
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The Human Journey Towards Spirituality. A Transformational Experience
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Midvastus and Medial parapatellar approaches for knee arthroplasty. A prospective comparative study of the midvastus and medial parapatellar approaches for total knee arthroplasty in the early postoperative period
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Consumers?attitudes towards differently branded pork products. A Means-End Chain analysis
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A test construction. Developing a scale for measuring perceived barriers to behavioral change towards HIV/AIDS prevention
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