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Органическая химия Органическая химия

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Stress-induced molecular changes in the mammalian brain Long-lasting stress-induced changes in neuronal alternative splicing.

Автор:   Eran M.
мягкая обложка
100 страниц
2009 год
Издательство:   Книга по Требованию
Цена:
2005 руб
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Описание:Meshorer focused on a particular mRNA - acetylcholinesterase (AChE), which is neuronally-expressed, stress-responsive, and yields alternatively spliced products, thus serving as an adequate model for this purpose. Ample information suggests multileveled relationships between long-term psychological stress responses and alternative splicing – the process which yields different mRNAs from the same gene. The book begins with an introduction covering the general areas of stress responses, their long-term consequences, the mechanism of splicing and alternative splicing, neuritic translocation of mRNAs and highlights the AChE gene and its protein products as putative mediators of such long-term consequences. Finally, the book ends with a discussion on the consequences of such responses, linking stress responses with aging. Eran Meshorer studied the stress-induced changes in alternative splicing at Hermona Soreq’s lab and shed light on the molecular pathways that lead to such responses. However, the nature of these relationships remains unclear. The results section depicts 3 works describing 3’ and 5’ alternative splicing of AChE and a potential mediator of the stress-induced responses.


Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка

2990 руб
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