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A System to Evaluate the Effect of Stress on Arterial Remodeling. Development of an Organ Culture System and its Implementation in Studying the Effects of Stress on Arterial Remodeling

Автор:   Zachary D.
мягкая обложка
156 страниц
2009 год
Издательство:   Книга по Требованию
Цена:
2413 руб
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Описание:Additional softening seen in arteries was attributed to the effects of the culture system. It was hypothesized that this softening was the result of a changing collagen structure. However, most studies utilize a methodology that controls the global parameters (pressure, flow rate, and axial stretch). The results of this study demonstrate the ability of a novel organ culture system to achieve and maintain target values of stress throughout the culture period. This approach often confounds the results since the actual drivers of remodeling are not independently isolated. Arterial remodeling is a process by which arteries respond to sustained changes in their mechanical environment. Cell viability, general arterial morphology, and collagen synthesis rates were maintained for all arteries. This process occurs in a way such that an artery’s local mechanical environment (circumferential, shear, and axial stress) is maintained at a homeostatic level. The elevated axial stress appeared to cause a softening of the artery in both the axial and circumferential direction.


Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка

2990 руб
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Kick Ass: Selected Columns of Carl Hiaasen

Scientists say its effects are spreading, and the prospects are dire: The collapse of a uniquely bountiful estuary, and the potential crippling of a multimillion-dollar tourist and fishing economy. There's no quick answer. Grass beds are sensitive and slow-growing; replenishment takes a long time. Part of the problem lies miles away, in the Everglades. For centuries the southward flow of fresh water emptied purely into Florida Bay. Then the geniuses who manage our canal systems began diverting water to benefit developers and farmers. That folly was implemented under the guise of "flood control." With its flow of fresh water disrupted, Florida Bay got saltier each season. The hypersalinity, combined with drought, caused drastic changes. Some biologists believe additional harm came from fertilizers and pesticides which flushed through the Everglades into the bay. What you now see out your car window is unlike anything that's happened before. From an airplane, the sight is even more dramatic and dismaying. In past years the blooms were smaller, localized ...»

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Магнитная планка самоклеющаяся, 100x5 см + 6 магнитов.
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