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Системный подход в социологии Системный подход в социологии
Основы социологии Основы социологии


The neuroprotective role of insulin Oxidative stress and diabetes on neuronal function and metabolism.

Автор:   Ana D.
мягкая обложка
276 страниц
2010 год
Издательство:   Книга по Требованию
3231 руб
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Описание:Herewith,we can find valuable tools (especially to Neuroendocrinologists,Neurochemists and Pharmacologists) to establish insulin as a promising therapeutic agent,particularly in normoglycemia conditions. In the last two decades insulin signalling and protection in brain has emerged as a novel field of research. Although growing evidence supports the hypothesis that dysfunction of neuronal glucose utilization and metabolism and/or in insulin receptor signal transduction cascade is involved in Alzheimer’s disease pathogenesis,the role of insulin on oxidative stress- and diabetes-induced neuronal dysfunction and death has been less investigated. More specifically,it is shown that insulin has a neuromodulatory role,and also that it activates neuronal receptor-mediated signalling,controlling antioxidant defences,glucose metabolism and preventing against apoptosis associated with oxidative stress. This book,therefore,provides new experimental evidences that reveal the cascade of events underlying the putative neuroprotective effect of insulin on neurotransmission,and neuronal function and survival associated with oxidative stress and diabetes.

Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка

2990 руб
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Английский язык для медиков

The major functional components of the res piratory system are: the airways, alveoli, and blood vessels of the lungs; the tissues of the chest wall and diaphragm; the systemic blood vessels; red blood cells and plasma; and respi ratory control neurons in the brainstem and their sensory and motor connections. LUNG FUNCTION: provision of O 2 for tissue metabolism occurs via four mechanisms. Ventilation the transport of air from the environment to the gas exchange surface in the alveoli. O 2 diffusion from the alveolar air space across the alveolarcapillary membranes to the blood. Transport of O 2 by the blood to the tissues: O 2 diffusion from the blood to the tissues. Removal of CO 2 produced by tissue metabolism occurs via four mechanisms. CO 2 diffusion from the tissues to the blood. Transport by the blood to the pulmonary capillaryalveolar membrane. CO 2 diffusion across the capillaryalveolar membrane to the air spaces of the alveoli. Ventilation the transport of alveolar gas to the air. Functional components: Conducting airways (conducting zone; anatomical dead space) ...»

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