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Органическая химия Органическая химия

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Computational Methods for Fragment Spectrum Interpretation. Computational Interpretation of Tandem MS Spectra Including Fragment Ions with Post-Translational Modifications

Автор:   Jonathan R.
мягкая обложка
56 страниц
2009 год
Издательство:   Книга по Требованию
Цена:
2005 руб
отсутсвует
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Описание:Finally, the algorithm is successfully applied on the fragment spectra in the PRIDE proteomics data repository to render it suitable for statistical machine learning investigations. The high number and diversity of known PTMs as well as suboptimal quality of spectra compromise the identification of PTMs in MS experiments. In this book, an efficient algorithm for the computational interpretation of tandem MS spectra including fragment ions with PTMs is described. Information on both precursor and fragment ion level is utilized and an arbitrary number of PTMs is considered. Post-translational modifications (PTMs) are of critical importance for a vast range of cellular processes such as growth control and signal transduction. A robust statistical noise intensity model is developed to compensate for low spectrum quality. However, interpretation of tandem MS spectra including fragment ions with PTMs from high-throughput experiments is a complex challenge. Mass spectrometry (MS) can shed light on the characteristics of PTMs to gain insight into the mechanisms of numerous diseases including cancer.


Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка

2990 руб
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Coders at Work: Reflections on the craft of programming

I got a listing of that and on vacation, Christmas or something, I read it and just dissected it. I didnБЂ™t know the language it was written in. which happened to be NELIAC. And it was just a marvelously written program. And I learned programming, NELIAC, Intercom, and how to interpret somethingБЂ”everythingБЂ”from that. I just sat and I read it for probably the entire vacation, a week. And then came back and asked him questions about it, nagging little bugs kinds of things. After that I knew how to program and I was pretty good at it. Then I got jobs programming. I was basically working my way through school, work-study and then odd jobs. I was a research assistantБЂ”a grunt for a graduate student to get programming done for his thesis. And I was a TA. I did programming for the computer center. Part of the computer-center stuff was to sit in a little booth and have people come in and say, БЂњI only changed one thing.БЂ« БЂњWell, letБЂ™s look at that one thing and see what happened to you.БЂ« Seibel: Did that hone your debugging skills or was it all just incredibly stupid stuff? Thompson: It honed that type of debuggingБЂ”you understood common errors really well after that ...»

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Защитный детский бальзам от ветра и холода "Weleda" с календулой, 30 мл.
Защитный бальзам от ветра и холода с календулой Weleda разработан, чтобы уберечь нежную кожу ребенка от погодных воздействий. Он может
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327 руб
Раздел: Классические игры


Quantum Transport in Carbon-based Nanostructures. Theory and Computational Methods
Following a detailed theoretical introduction, the work covers the effects of realistically modelled metallic contacts on the transport properties of nanotubes and -ribbons, ballistic magnetoresistance effects, the mesoscopic length scales in disordered and defective carbon systems, multilayer carbon systems, issues of approximate momentum conservation in incommensurate systems and the effects of external magnetic fields on the electronic structure of carbon systems.
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Experimental and Computational Aspects Growth of Bulk SiGe Single Crystals by Liquid Phase Diffusion Method.
The development of a macroscopic mixture model is presented to model the LPD growth system.
          3231 руб             2009 год          224 стр.          мягкая обложка

Computer Aided Design and Computer Aided Engineering (CAD-CAE). Methods, models and tools for CAD-CAE integration
In this book, a new approach is proposed to reduce the gaps between CAD and CAE software' s. There is based on new shape representation called mixed shape representation. This later supports simultaneously the B-Rep (manifold and non-manifold) and polyhedral representation, and creates a robust link between the CAD model (B-Rep NURBS) and the polyhedral model. The both representations are maintained on the same topology support called the High Level Topology (HLT), which represents a common requirement for simulation model preparation. The chapters cover the geometric models involved in CAD and CAE and the associated methods and tools for Finite element model generation. The software implementation of the integration between CAD and CAE is also developed in this book. The book is an excellent industrial reference, as well as a student text. As a result, models generated by CAD systems are often unsuitable for Finite Element Analysis (FEA) needs. Computer Aided Design (CAD) and Computer Aided Engineering (CAE) are two significantly different disciplines, and hence they require different shape models representations.
          3231 руб             2010 год          268 стр.          мягкая обложка

Statistical Methods in Computational Electromagnetism. Using Transmission Line Modelling
The case studies used are developed using the Transmission Line Modelling (TLM) method.
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Controlling of Large-Scale Systems with Special Regard to The Control of a Heat Power Station Soft Computing Method Based on Thom's Catastrophe Theory.
The goal of this work is to develop a new method to achieve higher efficiency and safety in controlling of large-scale systems by Thom' s catastrophe theory. The new method will be introduced by a large-scale system, the steam production technology which includes extremely fast and extremely slow processes. This requirement needs to use safety and fast bi-directional communication. Extremely slow processes require continuous communication with the process to perceive slow and fine changes, ability to distinguish a finite state of process from any temporary state of process, and capability to recognize and evaluate the relatively faster short- time events. Extremely fast processes require high-powered data collection and data conversion, high-speed process control system with extremely short real-time cycle, high computational capability, and high memory capacitance. The tool for this goal is the efficient and accurate real-time control. Technical development in industry requires a harmony between the controlled process, the control system and the human. Some technologies consist of extremely fast and extremely slow processes.
          2623 руб             2010 год          168 стр.          мягкая обложка

Das Versprechen: Fragment (на нем. яз) Requien auf den Kriminalroman; Aufenthalt in einer kleinen Stadt:
Mittlerweile ist aus Klari Wascher die Multimillionarin Claire Zachanassian geworden.
          395 руб             1998 год          206 стр.          Мягкая обложка

Essentials of research methods
The logic and techniques of research methods can be daunting and not of obvious use to students of social science, and yet this book clearly and coherently defines the terms and requirements of research methods studies for the inexperienced student.
          1430 руб             2004 год          256 стр.          мягкая обложка

Computational Kinematics
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Treaty Interpretation, the Constitution and the Rule of Law
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Spectrum 3
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Spectrum 3 Workbook 3A
          225 руб             1993 год

Spectrum 4 Teacher's Edition
          805 руб             1992 год

Spectrum 5
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Spectrum 6 Student Placement & Evaluation Packet (+ компакт-кассета)
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Handbook of Computational Economics vol 1
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          4351 руб             1996 год          832 стр.          твердый переплет

An Historical Interpretation Of Philosophy
          2 руб             1893 год          532 стр.          мягкая обложка

The Diagnosis Of Bee Diseases By Laboratory Methods
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          1139 руб             1916 год          236 стр.          мягкая обложка

Numerical Simulation of Gas Pipeline Networks: Theory, Computational Implementation, and Industrial Applications
These methods can be applied both at the stage of a pipeline network' s design and at the stage of its operation. They allow for the development of efficient automated hardware and software systems for the early detection and prevention of dangerous malfunctioning of a pipeline network. They can be of use for development and efficiency analysis concerning anti-terrorist activities at big industrial energy plants. Practical applications of computation technologies and methods of numerical simulation are illustrated with examples of solving industrial problems for gas industry enterprises. The authors demonstrate the efficiency of these technologies and the methods for improving the safety of the oil pipeline networks serving thermal power stations. The book is intended for scientists and engineers who deal with the design of pipeline networks, the analysis of their actual state, pipeline network insurance and control, improving their industrial safety and environmental friendliness, in the context of a wide range of environment-oriented measures. The material is also comprehensible to graduate students in technical high schools. The application of these methods and technologies is aimed at an integrated assessment of the state of the gas pipeline networks of industrial enterprises and the creation of efficient safe modes for their operation. The book considers computation technologies and methods for numerical simulation intended for solving the problems of improving the operational safety and the efficiency of industrial gas pipeline networks. This approach is based on modern methods of computational mechanics and mathematical optimization.
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Aeroelastic Analysis of Micro Air Vehicles. Coupled Computational and Experimental Techniques
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          1978 руб             2009 год          104 стр.          мягкая обложка

Analysis and Measurement on Terrestrial DTV Radio-Wave Coverage. Basics, Methods, Criteria, Expertise
A complete set of field measurement and analyzing scheme is essential for verifying if the DTV signals are effectively received by local consumers.
          2744 руб             2009 год          188 стр.          мягкая обложка

Exploring the City with Bourdieu. Applying Pierre Bourdieu’s theories and methods to study the community Foreword by Loic Wacquant
It has become the oil capital of Norway.
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Computational Neural Models for Body Surface ECG Data Analysis. Body Surface Cardiac Mapping
Secondly, since MI is localised on the torso surface, and due to the high number of electrocardiographic leads involved in BSCM, it is desirable to find an optimal reduced lead set for acute MI detection.
          3188 руб             2009 год          204 стр.          мягкая обложка

Synthetic Unit Hydrographs in the Upper Awash and Tekeze Basins. Methods, Procedures and models
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          2382 руб             2009 год          124 стр.          мягкая обложка

Computational Case-based Redesign for People with Ability Impairment. Rethinking, Reuse and Redesign Learning for Home Modification Practice
A redesigner alters existing structures, fittings and fixtures to better meet the occupants ability requirements.
          3188 руб             2008 год          316 стр.          мягкая обложка

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