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SUSTAINED RELEASE TABLET OF CARDIOVASCULAR DRUG BY MELT GRANULATION. An advanced granulation technique

Автор:   Durgacharan B.
мягкая обложка
88 страниц
2010 год
Издательство:   Книга по Требованию
Цена:
1891 руб
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Описание:Oral administration has been most versatile convenient and commonly employed route of drug delivery. But these methods have number of disadvantages such as number of steps, equipments, labors, wastage of materials hence costly. Today' s Pharmaceutical industry require minimum step, simple, continuous and efficient method. Melt granulation offers several advantages compared to conventional granulation since the liquid addition and subsequent drying step are omitted. Thus process is less consuming in terms of time and energy compared to other methods. Hence in this book an attempt has been made to develop sustained release tablet of Verapamil HCl using some lipophilic binders by melt granulation technique. Also effect of different process parameters such as concentration and type of lipophilic binders, methods of preparation, stirring time and different release enhancers on drug release was studied. Sustained release drug delivery system have started gaining popularity and acceptance as new drug delivery system due to better control over release for extended time. Conventionally there are two types of granulation methods i. e. wet and dry granulation.


Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка

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Incest girl

Her hips ground down hard as his searching tongue found and centered on her hard clitoris a few seconds before his mouth circled it and he concentrated all his efforts on making his baby daughter explode in a climax unlike any she would ever know again. That first climax – the very first time a boy or girl reaches for and attains the stars, is an experience which can never again be equaled without the implication of drugs. He felt her pussy melt and enfold his entire mouth. Every fiber of her body shuddered, her breath came in short, ragged gasps as her cunt seemed to rob her of the very breath she needed to sustain life. Many, many times in his life, Alan had sucked women to a climax. But never once had he sucked a cherry pussy, and, of course, he'd never before sucked his own daughter's cunt. Her being a virgin could have had something to do with the tremendous flow from her convulsing snatch. Other pussies he'd sucked had gotten very wet during their climaxes, but never anything near the release from the pussy he was now sucking ...»

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