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Sex, Pregnancy and Estrogen Responsive Genes Critical Mediators of Multiple Sclerosis Disease Suppression.

Автор:   Na T.G.
мягкая обложка
120 страниц
2009 год
Издательство:   Книга по Требованию
Цена:
1978 руб
отсутсвует
на складе

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Описание:The studies outlined in this book offer findings that support therapeutic advancement for all forms of MS with a thorough investigation of factors that guide disease susceptibility and clinical progression. Pregnancy suppresses MS severity in human and animal models. Females are three times as likely as males to be affected, but males often present with a more severe disease course. Patients present with a myriad of symptoms making MS difficult to diagnose. PI3Ks are involved in cellular trafficking, growth and death. This is likely due to hormone and genetics regulation of proteins involved with inflammation such as PI3K proteins. Sex dimorphism and pregnancy changes have been noted in both MS and experimental autoimmune encephalomyelitis, a commonly used animal model for MS. These models aid in research development and improve the understanding of immunological processes of the disease. Multiple sclerosis (MS) is a chronic demyelinating disease of the CNS affecting nearly 3 million people world-wide. Clinical presentation of MS ranges from mild to severe, and no two patients can be said to demonstrate the same clinical course.


Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка

2990 руб
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Autism in Northern Finland. European Child & Adolescent Psychiatry 2000; 9:162-167. 83 Nuutinen H. et al. Incidence and prevalence of Crohn s disease in Finland from 1986 to 1991. Gastroenterology, vol. 112:4. 84 Письмо в BMJ Перевод А. Казачек. 85 См. соч., указ. в прим. 2, с. 271. 86 Alter М. Is multiple sclerosis an age-dependent host response to measles? Lancet Feb 1976; 1:456-7 87 Nakayama T. et al. Long-term regulation of interferon production by lymphocytes from children inoculated with live measles virus vaccine. J. Infect. Dis. 1988 Dec; 158(6): 1386-90. 88 Yalcin S.S. The effect of live measles vaccines on serum vitamin A levels in healthy children. Acta. Paediatr. Jpn. 1998 Aug; 40:345-9. 89 Hutchins S. et al. Measles outbreaks in the United States 1987 through 1990. Paediatr. Infect. Dis. J. 1996;15:31-8 90 FDA Workshop to Review Warnings: Use Instructions and Precautionary Information [on Vaccines] Rockville, Maryland, Sept. 18, 1992, p. 37. 91 Orenstein W.A. et al. Rubella vaccine and susceptible hospital employees ...»

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