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Air flow and particle deposition. Patterns in the diseased human lung

Автор:   Rebecca S.
мягкая обложка
124 страниц
2010 год
Издательство:   Книга по Требованию
Цена:
2277 руб
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Описание:Computational flow models are used to model two different airway diseases, chronic obstructive pulmonary disease (COPD) and bronchial tumors. Patients with compromised lung function are more sensitive to air pollution; understanding the extent of that sensitivity can lead to more effective air quality standards. In particular we are interested in how the motion of particulate matter and air is affected by the presence of lung disease. This indicates the need for different protocols regarding susceptibility of people to airborne pollutants that take into account lung disease. The presence of disease in the lung has a large effect both on global deposition patterns and on localized airflow patterns. This work is an investigation of particle deposition and air flow in the human lung. It also suggests that treatment should account for changes in airflow in the diseased lung. Also, understanding of air flow and particle trajectories could lead to the development of better aerosol drugs to treat the lung diseases.


Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка

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Low lung volumes lead to increased airway resistance because there is less traction on the airways. At very low lung volumes, bronchioles may collapse. The viscosity or density of inspired gases can affect airway resistance. The density of gas increases with deep sea diving, leading to increased resistance and work of breathing. Low-density gases like helium can lower airway resistance During a forced expiration, the airways are compressed by increased intrathoracic pressure. Regardless of how forceful the expiratory effort is, the flow rate plateaus and cannot be exceeded. Therefore, the air flow is effort-independent; the collapse of the airways is called dynamic compression. Whereas this phenomenon is seen only upon forced expiration in normal subjects, this limited flow can be seen during normal expiration in patients with lung diseases where there is increased resistance (e. g., asthma) or increased compliance (e. g., emphysema). New words intrapleural внутриплевральный intra-alveolar внутриальвеолярный collapse коллапс viscosity вязкость density плотность 32.PMechanics of breathing Muscles of respiration: inspiration is always an active process ...»

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